Spaniard qualifier Bernabe Zapata Miralles won against American John Isner, the No 23 seed, 6-4, 3-6, 6-4, 6-7 [5], 6-3 to move into the last 16 of Roland-Garros.
Zapata Miralles, ranked No 131, will play the winner of the next match between German Alexander Zverev, the No 3 seed, and American Brandon Nakashima next.
The Spaniard defeated Israeli Dudi Sela (6-3, 6-0), Portuguese Gastao Elias (6-1, 6-1), Italian Luca Nardi (3-6, 6-4, 6-1), American wildcard Michael Mmoh (7-6 [7], 6-3, 7-5) and American Taylor Fritz, the No 13 seed (3-6, 6-2, 6-2, 6-3) to get to this point.
Earlier in the tournament, Isner, ranked No 26, edged out Frenchman Quentin Halys (7-6 [3], 4-6, 7-6 [1], 7-6 [6]) and Frenchman wildcard Gregoire Barrere (6-4, 6-4, 3-6, 7-6 [5]).
Paris (Grand Slam): Other third-round results (Stade Roland-Garros, clay, EUR 43.600.000, most recent results first):
- Rafael Nadal (5) beat Botic van de Zandschulp (26): 6-3, 6-2, 6-4
- Novak Djokovic (1) beat Aljaz Bedene: 6-3, 6-3, 6-2
- Felix Auger-Aliassime (9) beat Filip Krajinovic: 7-6 [3], 7-6 [2], 7-5
- Diego Schwartzman (15) beat Grigor Dimitrov (18): 6-3, 6-1, 6-2