2021 MLB odds, picks, best bets for May 12 from proven model: This four-way parlay pays 14-1

Brandon Woodruff attempts to bounce back from his first loss of the 2021 MLB season when he starts for the Milwaukee Brewers against the visiting St. Louis Cardinals on Wednesday at American Family Field. Woodruff gave up just one run and two hits while registering 11 strikeouts over 6 2/3 innings at Philadelphia on Thursday, but received no support in a 2-0 defeat. The 28-year-old has allowed fewer than three runs while working at least six frames in each of his last six starts. Should you expect another strong effort from Woodruff on Wednesday, or is there value in the Cardinals getting to the right-hander and bringing a return on the money line?

The latest MLB odds for Wednesday from William Hill Sportsbook list the Brewers at -172 (risk $172 to win $100) against the Cardinals. Other MLB lines of note include the New York Yankees at -195 against the Tampa Bay Rays and the Atlanta Braves listed as slight money-line favorites (-115) versus the Toronto Blue Jays. Before making any MLB picks or predictions on those games or others, you need to see the MLB predictions and betting advice from the SportsLine Projection Model.

This model, which simulates every pitch of every game 10,000 times, had a banner 2019 season, the league’s last full schedule, returning more than $1,400 on its top-rated money-line and run-line MLB picks. It is off to a fast start in 2021, going 44-31 on top-rated MLB money-line picks through six weeks, returning more than $700. Anyone following it has seen huge rewards.

Now, the model has evaluated the latest MLB lines for Wednesday and posted its best bets for the evening games. Parlaying these four MLB picks would pay 14-1. Head to SportsLine to see the picks. 

Top MLB picks for Wednesday, May 12

One of the MLB picks the model loves for Wednesday: the model is high on the Chicago White Sox (-140) to beat the Minnesota Twins. Chicago is riding a four-game winning streak after erasing a three-run deficit en route to a 9-3 victory in Tuesday’s series opener. Yasmani Grandal and Jose Abreu each homered while combining to go 3-for-7 with five RBIs and four runs scored in the triumph. Abreu has driven in five runs while posting back-to-back multi-hit performances and has recorded nine RBIs over his last six contests.

Tim Anderson added two hits and an RBI on Tuesday and enters with a six-game hitting streak. The 2019 American League batting champion has enjoyed success against Minnesota starter J.A. Happ during his career, going 9-for-16 with a pair of home runs and four RBIs. In 63 career games against the Twins, Anderson is hitting .320 with eight homers and 26 RBIs – his third-highest total versus any team.

Featured Game | Chicago White Sox vs. Minnesota Twins

How to make MLB predictions, parlays for Wednesday, May 12

The model has locked in three other MLB best bets, including one on a surprising underdog. You can see the best bets only at SportsLine.

So which MLB picks should you make on Wednesday for a shot at a big return of 14-1? And which surprising underdog do you need to be all over? Visit SportsLine now to see Wednesday’s MLB picks, all from the projection model off to a fast start in 2021, and find out.